In feature films, Melissa has worked with Dennis Quaid and Jim Caviezel in the surrealistic drama Frequency, and with Angelina Jolie as her best friend and sidekick in the romantic comedy romp Life or Something Like It. In the film Loverboy, directed by Kevin Bacon, she plays opposite Kyra Sedgewick. Melissa has chosen strong and challenging films on subjects as varied as thrillers, family drama and comedy. She has played a ditzy sloppy newscaster, a scientist, a righteous schoolteacher, as well as a heartrending ghost and an Italian artist intellectual. She has worked with esteemed directors such as Jon Favreau, Spike Lee, Don Scardino, and Ed Burns.